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Author (up) Choi, Y.S.; Koo, E.S.; Kim, M.S.; Choi, J.D.; Shin, Y.; Jeong, Y.S. doi  openurl
  Title Re-emergence of a GII.4 Norovirus Sydney 2012 Variant Equipped with GII.P16 RdRp and Its Predominance over Novel Variants of GII.17 in South Korea in 2016 Type Research Support, Non-U.S. Gov't
  Year 2017 Publication Food and environmental virology Abbreviated Journal Food Environ Virol  
  Volume 9 Issue 2 Pages 168-178  
  Corporate Author Thesis  
  Address Department of Biology, College of Sciences, Kyung Hee University, Seoul, Republic of Korea. ysjeong@khu.ac.kr  
  Keywords Australia/epidemiology; Caliciviridae Infections/*virology; Disease Outbreaks; Gastroenteritis/epidemiology/*virology; Genotype; Humans; Norovirus/classification/genetics/*isolation & purification/physiology; Phylogeny; Republic of Korea/epidemiology; *Gii.4; *Gii.P16; *Norovirus; *RdRp; *Viral surveillance  
  Abstract Noroviruses are major causative pathogen of nonbacterial acute gastroenteritis worldwide. Of the seven genogroups of noroviruses suggested recently, genogroup II genotype 4 (GII.4) had been the most common genotype identified in hospitalized patients in the last few decades. However, since the latter half of 2014, new variants of GII.17 have been reported as the main causes of outbreaks over GII.4 in East Asia and have also occurred in America and Europe. In this study, we monitored norovirus GII in coastal streams at South Gyeongsang province and South Jeolla province of South Korea from March 2015 to May 2016. Norovirus GII.17 capsid sequences were predominantly detected until September 2015 in water samples. However, we found that the number of positive cases of the norovirus GII.4 Sydney 2012 capsid sequence has been increasing since December 2015, overtaking that of GII.17 in 2016. The RdRp genotype of this predominant GII.4 variant in 2016 was identified as GII.P16. The emergence and predominance of the GII.4 pandemic capsid sequence harboring a different RdRp genotype suggested the potential for a future pandemic.  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 1867-0334 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:28120262 Approved no  
  Call Number NCSU @ edshirle @ Serial 3522  
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