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Author (up) Aho-Laukkanen, E.; Hirvonen, J.J.; Saha, K. doi  openurl
  Title Comparison of Xpert Norovirus and RidaGene Norovirus assays for the detection of noroviruses in clinical fecal specimens Type Journal Article
  Year 2017 Publication European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology Abbreviated Journal Eur J Clin Microbiol Infect Dis  
  Volume 36 Issue 6 Pages 1019-1022  
  Corporate Author Thesis  
  Address Clinical Microbiology, Seinajoki Central Hospital, Hanneksenrinne 7, P.O. Box 7, 60220, Seinajoki, Finland  
  Keywords Caliciviridae Infections/*diagnosis/virology; Feces/*virology; Humans; Molecular Diagnostic Techniques/*methods; Norovirus/genetics/*isolation & purification; Predictive Value of Tests; Sensitivity and Specificity  
  Abstract The purpose of this study was to investigate the usability and performance of the Xpert Norovirus and RidaGene Norovirus assays for the detection of noroviruses in fecal specimens. Of the 186 stool specimens, 53 (28.5%) were considered true-positive for norovirus (NoV). Of the true-positive specimens, Xpert detected 53 and RidaGene detected 52. The respective sensitivity and specificity were 100% and 94.7% [95% confidence interval (CI), 91.0-98.5%] for the Xpert assay, and 98.1% (95% CI, 94.4-100%) and 97.0% (95% CI, 94.1-99.9%) for the RidaGene assay. Positive and negative predictive values (PPVs and NPVs) were 88.3% and 100% for the Xpert assay, and 92.9% and 99.2% for the RidaGene assay, respectively. Based on this study, it can be concluded that there were no significant differences (p-value > 0.5) between the results of the Xpert and RidaGene Norovirus assays. We found that both assays are useful for the detection of noroviruses in clinical stool samples.  
  Publisher Place of Publication Editor  
  Language English Summary Language Original Title  
  Series Editor Series Title Abbreviated Series Title  
  Series Volume Series Issue Edition  
  ISSN 0934-9723 ISBN Medium  
  Area Expedition Conference  
  Notes PMID:28063001 Approved no  
  Call Number NCSU @ edshirle @ Serial 3494  
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