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Author (up) Alhatlani, B.; Vashist, S.; Goodfellow, I.
Title Functions of the 5' and 3' ends of calicivirus genomes Type Research Support, Non-U.S. Gov't
Year 2015 Publication Virus research Abbreviated Journal Virus Res
Volume 206 Issue Pages 134-143
Corporate Author Thesis
Address Division of Virology, Department of Pathology, Addenbrooke's Hospital, University of Cambridge, Cambridge CB2 2QQ, UK. Electronic address: ig299@cam.ac.uk
Keywords Caliciviruses; Norovirus; RNA secondary structures; RNA-protein interactions
Abstract The Caliciviridae family of small positive sense RNA viruses contains a diverse range of pathogens of both man and animals. The molecular mechanisms of calicivirus genome replication and translation have not been as widely studied as many other RNA viruses. With the relatively recent development of robust cell culture and reverse genetics systems for several members of the Caliciviridae family, a more in-depth analysis of the finer detail of the viral life cycle has now been obtained. As a result, the identification and characterization of the role of RNA structures in the calicivirus life cycle has also been possible. This review aims to summarize the current state of knowledge with respect to the role of RNA structures at the termini of calicivirus genomes.
Publisher Place of Publication Editor
Language English Summary Language Original Title
Series Editor Series Title Abbreviated Series Title
Series Volume Series Issue Edition
ISSN 0168-1702 ISBN Medium
Area Expedition Conference
Notes PMID:25678268 Approved no
Call Number NCSU @ edshirle @ Serial 3115
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